Solution for micro-array- and PCR-based assays and Molecular Diagnostics
Molecular Diagnostics is a technique rapidly evolving alongside the historical protein Elisa-type detection technique. It is generally admitted now that molecular diagnostics will become instrumental to the implementation of new domain of activities such as point of care diagnostics. Molecular diagnostics has the potential to deliver robust, reliable and agile solutions for field diagnostics in human, animal, plant heath, agro-food, bio-defence and water sectors. Micro-arrays:Based on its unique expertise and know-how in that field (lien vers “Technology and Know-how” BioXpr can deliver the following solutions for research-based activities or for molecular diagnostic kits design:· design of the oligonucleotides to be spotted on customized low and medium density micro-arrays,· design of low and medium density micro-arrays,· biostatistical analysis of low, medium and high-density (Affymetrix, Agilent,... ) micro-arraysMore generally speaking BioXpr is also capable of creating from scratch a global bioinformatics environment to support the design, the production, the IP search and the quality control activities of low to medium density micro-arrays.BioXpr has teamed-up with the company DNAVision in 2009 to offer a seamless service (from experimentation through to data analysis and interpretation) for low (customized) and high-density micro-arrays (Affymetrix, Agilent,...). More in on that collaboration at (mettre le lien vers “Partnership, DNAVision”)For more info on our capabilities please contact us at (lien vers “Contacts”)Case Study: (same case-study as in the “Technology and Know-how” part) PCR- Polymerase Chain reaction:Based on its unique expertise and know-how in that field (lien vers “Technology and know-how”) BioXpr provide both services and product in that field for research-based activities or for molecular diagnostic kits or instrumentation design.As service provider BioXpr can deal with any type of nucleotides (DNA, RNA, LNA, PNA,...) to predict primers and probes such as TaqMan, TaqMan-MGB, Molecular Beacon, Scorpions, MLPA,...BioXpr is also expert in analysing, discriminating and optimizing the PCR-based response-curves to ensure better detection limits. Bioxpr can also optimize the detection time of the PCR reaction by optimum design of the related primers. Different case study form presentation(same case-study as in the “Technology and Know-how” part) As product developer BioXpr has successfully launched in 2009 a unique software called BioXpress to predict PCR Primers and TaqMan, TaqMan-MGB and Molecular Beacon probes. Subsequent versions will deal with other type of probes and multiplex approaches. For more info .. (lien vers “BioXpress”) For more info on our capabilities please contact us at (lien vers “Contacts”)
